Simple predictive model for early childhood caries of chilean children / Simple predictive model for early childhood caries of chilean children.

INTRODUCTION: Early Childhood Caries (ECC), in both industrialized and developing countries, is the most prevalent chronic disease in childhood and it is still a health public problem, affecting mainly populations considered as vulnerable, despite being preventable. Objective The purpose of this study was to obtain a simple predictive model based on risk factors for improving public health strategies for ECC prevention for 3-5 year-old children. Methods - Clinical, environmental and psycho-socio-cultural data of children (n=250) aged 3-5 years, of both genders, from the Health Centers, were recorded in a Clinical History and Behavioral Survey. Results-24

of children presented behavioral problems (bizarre behavior was the main feature observed as behavioral problems). The variables associated to dmf ?4 were: bad children temperament (OR=2.43 [1.34, 4.40]) and home stress (OR=3.14 [1.54, 6.41]). It was observed that the model for male gender has higher accuracy for ECC (AUC= 78

, p-value=0.000) than others.Conclusions- Based on the results, we proposed a model where oral hygiene, sugar intake, male gender, and difficult temperament are main factors for predicting ECC. This model could be a promising tool for cost-effective early childhood caries control.

Concentración de proteínas totales en saliva de jóvenes consumidores sociales de alcohol / Total protein concentration in saliva alcohol social young consumers

La concentración de proteínas salivales, así como el flujo salival, puede ser afectada por el consumo crónico de alcohol a través de la alteración estructural que éste produce en las glándulas secretoras. Aunque existen antecedentes acerca de una modificación en la concentración de proteínas salivales como consecuencia de la ingesta aguda de etanol, no se hallaron referencias sobre los efectos del consumo social del mismo. Por ello, el objetivo del presente estudio fue analizar la concentración de proteínas totales en saliva de jóvenes consumidores sociales de alcohol, las cuales son imprescindibles para mantener el estado de salud de los tejidos dentarios y peridentarios. Participaron treinta estudiantes universitarios de ambos sexos, de 18-25 años de edad, clínicamente sanos, con y sin antecedentes de consumo de alcohol. Los mismos respondieron a un cuestionario referido al consumo de alcohol y tabaco, administración de medicamentos y presencia de enfermedades sistémicas. Se obtuvieron muestras de saliva mixta no estimulada, en condiciones de ayuno y mediante la técnica de expectoración. Luego de centrifugar las muestras, la concentración de proteínas fue analizada por Lowry modificado y el perfil de proteínas por SDS PAGE 12 por ciento. El consumo de alcohol se encontró estadísticamente correlacionado con el hábito de fumar (p=0,0001) y el sexo masculino (p=0,01). La concentración de proteínas totales salivales (g/l) fue significativamente diferente entre los grupos de consumidores y no consumidores de alcohol (p=0.04), con una mayor concentración promedio en el grupo de no consumidores en relación a las variables sexo, tabaco y medicación. Los resultados del presente estudio permiten concluir que el consumo social de alcohol modifica la concentración de proteínas totales de la saliva

The concentration of salivary proteins, as well as the salivary flow, may be affected by the chronic alcohol intake through the structural changes it induces in the secretory glands. Although the modification in salivary protein concentration as a result of acute alcohol intake has been reported, no references were found on the effects of its social intake. Thus, the main purpose of this study was to analyze the concentration of total proteins in saliva of young social alcohol consumers, which are necessary to maintain the healthy condition of dental and peridental tissues. Thirty University students of both sexes, age range18-25 years old, apparently healthy, with and without (control) background of alcohol intake, participated in the study. They answered a questionnaire referred to the alcohol intake and tobacco smoking, medicine intake and presence of systemic diseases. Non-stimulated mixed saliva was obtained in fast condition and through the expectoration technique. After centrifuging the samples, the protein concentration was analyzed by modified Lowry and protein profile by electrophoresis 12 percent SDS PAGE. The alcohol intake was statistically correlated to tobacco smoking (p=0,0001) and masculine sex (p=0,01). The concentration of total salivary proteins was significantly different between the consumer and non-consumer groups (p=0.04), the highest mean concentration found in the second group in relation to sex, tobacco smoking and medicine intake. The results of the present study allow to conclude that the social alcohol intake modify the concentration of total salivary proteins